|
中国生物工程杂志 2008
Cyclodextrin and Its Derivatives as Non-viral Gene Vectors
|
Abstract:
Cyclodextrin (CD) is gradually applied in the nonviral gene vector system, due to its biocompatibility and flexibility of tailing via structural modification, polymerization or supramolecular combination. This paper reviews the ideas and research progress of the CD, its low molecular derivatives, CD polymers and CD supramolecular combination in the field of norviral gene vectros, and discuss their "structure - safety - transfection efficiency" relationships.