Anti-inflammatory activity of the lipid extract of Mytilus crassitesta
厚壳贻贝脂溶性提取物抗炎生物活性研究

The anti-inflammatory activity of the Mytilus crassitesta lipid extract was investigated by using tissue hyperplasia assay and adjuvant arthritis model in rats. The results showed that the Mytilus crassitesta lipid extract had significant anti-inflammatory activity. The tissue hyperplasia was significantly inhibited and primary and secondary symptoms of adjuvant-induced arthritis were significantly alleviated in Mytilus crassitesta lipid extract treatment group compared with vegetable oil group. The anti-inflammatory activity of the Mytilus crassitesta lipid extract was comparative with Lyprinol, a lipid extract of New Zealand green-lipped mussel (Perna canaliculus). Present study provides theoretical basis for exploitation of Mytilus crassitesta as functional food with anti-inflammatory activity or effective and safe anti-inflammatory drugs.