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遗传 2007
Theory and application of marker-assisted introgression
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Abstract:
Marker-assisted introgression(MAI) is one of the major applications of molecular information in animal breed-ing aiming at introgression of one or more favorable genes from a line(donor) to another(recipient),while keeping the genetic background of the recipient as much as possible.It consists of three phases.Firstly,cross donor and recipient lines to produce F1;secondly,repeated backcross the F1 individuals and the subsequent progenies with the recipient to recover its genetic background;and thirdly,intercross the backcrossed progenies to fix the introgressed genes in the population.Many factors affect the efficiency of MAI,among which the methods of foreground and background selection are very critical.