Polymorphisms of NQO1, CYP 1A1, mEH Genes
南京市正常人群NQO1、CYP1A1、mEH基因的多态性研究 Polymorphisms of NQO1, CYP 1A1, mEH Genes?in Normal Nangjing Population

The polymorphisms of NQO1, CYP1A1, mEH -Exon3,and mEH -Exon4 genes in normal Nanjing population (88 cases) were investigated by PCR approach. The results showed that the population frequency distributions of genotypes of wild-type,heterozygote, homozygous variant were respectively: NQO1 29.5%,51.1%,19.3%; CYP1A1 35.2%,44.3%,20.5%; mEH -exon3 26.1%,56.8%,17.0%; mEH -exon4 83.0%,15.9%,1.1%. The frequency distributions of genotypes in Nanjing population differ from those of other countries and do not show marked differences compared with other different area in Chinese population. The ethnic difference might be an important reason which results in the differences of related genotypes.