Genetic polymorphism of ten X-STR loci in naxi population
云南纳西族10个X-STR基因座遗传多态性研究

We studied the genetic polymorphism and haplotypes of ten short tandem repeats(STR) loci on the X chromo-some in Yunnan Naxi population.Genotyping and detection of PCR products from the ten X-STRs were carried out on de-naturing polyacrylamide gel electrophoresis followed by silver staining.The results revealed that among 98 males from Yunnan Naxi population,the number of alleles in the 10 loci(DXS7423,DXS7424,DXS6799,DXS7133,DXS6804,DXS8378,HPRTB,DXS7130,DXS7132 and DXS6789) were 4,7,6,3,6,5,5,7,6 and 8,respectively.Gene frequencies ranged from 0.0102(DXS7132 and DXS6789) to 0.7347(DXS7133).A total of 20 haplotypes were detected in DXS8378 and DXS7130 loci,and 56 haplotypes were detected in DXS6789,DXS6799 and DXS7424 loci.The haplotype diversity reached 0.8553 and 0.9649,respectively.In conclusion,the 10 X-STR loci are relatively abundant in polymorphic informa-tion for forensic identification,paternity testing and for genetic population studies.