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遗传 2001
Environment, Genome and Cancer
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Abstract:
Cancer is one of the most serious diseases that thre aten human being today.To some degree,it is a genetic disease but environmental and other nongenetic factors clearly play a role in many stages of neoplastic pr ocess.Genetic factors by themselves are thought to explain only about 5% of all cancer.The remainder can be attributed to external,“environment” factors that act in conjunction with both genetic and acquired susceptibility.Of note,part of the susceptibility is owing to the variety of human genome.So,environment,human genome and cancer have much to do with each other.Combining all of the informat ion from epidemiology and from research works in laboratory with policy-making and clinical works,purifying the environment,giving special protection to the po pulation at high risk,the mobility of cancer may decrease gradually in the futur e.