Chromosome Localization and Genomic Organization of Five Novel Human Genes Related to Cell Growth Control
人细胞生长相关5个新基因的染色体定位及其基因结构 Chromosome Localization and Genomic Organization of Five Novel Human Genes Related to Cell Growth Control

Five novel human genes related to cell growth control were newly isolated and identified by high-throughput functional screening.In this paper,the chromosomal localization of these five genes is reported.Radiation hybrid mapping and in silico mapping,and their genomic organization were analyzed respectively.PP3898 and PP1158 were assigned to chromosome 19p13.3,SP260 and PP753 to chromosome 1q21.1,and HC56 to chromosome 17p13.3.PP3898 contains nineteen exons and eighteen introns,PP1158 seven exons and six introns,SP260 ten exons and nine introns,and HC56 only one exon.The implications of chromosomal localization are discussed.