Advance in Bone Morphogenetic Protein-15 Gene
骨形成蛋白15基因的研究进展 Advance in Bone Morphogenetic Protein-15 Gene

Bone morphogenetic proteins (BMPs) are secreted signalling molecules belonging to the transforming growth factor-beta (TGF-beta) surperfamily. Up to date,more than 30 members of BMPs are identified. Bone morphogenetic protein-15 is only expressed in oocytes. Oocyte-specific BMP-15 might promote follicle growth in vivo, while preventing premature luteinization. This paper briefly discusses the progress in the research area of BMP-15 gene being as a candidate gene for litter size.