Transposable Element mariner
转座元件mariner Transposable Element Mariner

Mariner and mariner-like elements (MLEs) have been found in a wide range of organisms including human since its discovery in Drosophila mauritiana.MLEs belong to the mariner/Tc1 superfamily,one of the most diverse and widespread Class II transposable elements.MLEs have a conserved "D,D(34)D" motif in their transposases and they transpose by cut-and-paste mechanisms.Their extraordinarily wide host range and horizontal transmission in distantly related species indicate that they do not need additional host-specific factors for transposition.The evidence that MLEs could transform a wide variety of organisms especially the vertebrates supported the host-independent mechanism and suggested the availability as a kind of potential transforming vector.