Study of Microspectroscopy for the Position of the Fragile Sites in Human Chromosome
人染色体脆性位点部位的显微光谱学研究 Study of Microspectroscopy for the Position of the Fragile Sites in Human Chromosome

The position of fragilc sites in human chromosome was studied by means of the microspectroscopy. The results show that the amount of DNA in chromosome with fragile sites decreasesin most condition. We can suppose that the fragile sites of chromosome is caused by the superhelix structure changes of chromatin DNA during the formation of metaphase chromosome which is formed in high condensation.