Brain Dysfunction in Obsessive-Compulsive Disorder
强迫症的脑功能障碍

The phenomenological explanation for symptoms of OCD emphasized the malfunctioning processes involving in error recognition, as well as emotional and motivational functions in a special situation. The evidences from neuroanatomy, neurophysiology, especially recently from neuropsychology and neuroimaging studies of OCD suggest that: the functional overactivities in OFC and ACC could be responsible for the increased functions of error recognition and evaluation of emotion and motivation; the functional hypoactivity in DLPC could result in the lack of cognitive integration of the consequence of action. These cortical informations are converged by the caudate nucleus, which controls behavioral programs. Dysfunctions at one or several stages of the networks formed by these structures could lead to the emergence and maintenance of repetitive thoughts and characteristic OCD behaviors.