In vivo Bioactivity of Ti/HA Bio composites Fabricated by Powder Metallurgy Methods
粉末冶金法制备Ti/HA生物复合材料的体内生物活性

Ti/HA biocomposites were successfully fabricated by the powder metallurgy method. The in vivo bioactivities of the biocomposites were investigated. At an early stage of implantation, a fibrous film forms around the pure titanium implant. And with the increase of implantation time, the fibre tissue disappears gradually, accompanying the formation of new bone. After 6-month implantation, a typical bone-contact interface forms between the pure titanium implant and the surrounding bone. A very thin film of new bone is observed around the composite with 30% titanium and a big gap exists between the composite and the surrounding bone at an early stage of implantation, whereas, large quantity of new bone forms around the composites with 50% and 70% titanium. These three composites all form tight bone-bonding interface with the surrounding bone after 6-month implantation. So it can be concluded that these Ti/HA composites all exhibit excellent bioactivity. The osteogenic rate of the composite with 30% titanium is distinctly lower than that of the other two Ti/HA composites. The three Ti/HA composites all have better bioactivity than pure titanium.