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物理学报  2002 

The localization of multiple current dipoles in a realistic head shape model
真实头模型中的多电流偶极子脑磁源定位

Keywords: MEG,realistic head model,multiple dipoles,optimal method
脑磁技术
,真实头模型,多偶极子脑磁源,优化方法

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Abstract:

The realistic head model has been used in magnetoencephalography (MEG) as an accurate forward model for calculating the external magnetic fields resulting from neural activity.In this paper,we present a general matrix formulation for calculating the localization of multiple dipoles in a realistic head model by means of boundary element method.In addition,using general optimal combined with local optimal method,we solve the inverse problem by computer simulation.We simulate from the simple one dipole situation to the complicated five dipoles situation.The results prove that our method is of validity.In order to improve the rapidity of convergence as well as keep the localization precision,we use spherically symmetric conductor model in the general optimal method step if there is only 1 or 2 dipoles.

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