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微生物学报 2011
Diversity of cultured actinomycete in the Baltic Sea
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Abstract:
Objective] Actinomycetes(actinobacteria) are getting more and more recognized as a natural source for new drug exploration.In order to find new lead compounds,the diversity and selected bioactivities of cultured actinomycetes in the Baltic Sea(Germany) were investigated.Methods] One hundred sediment samples were collected from south of the Baltic Sea,of which 809 purified cultures of actinomycetes were obtained by using 7 media.The phylogenetic analysis of 280 selected strains based on 16S rRNA gene seque...