|
微生物学报 2011
Research advances in global regulator LaeA of filamentous fungi--a review
|
Abstract:
Global regulators play an important role in secondary metabolite biosynthesis and morphological development in filamentous fungi.LaeA,a key global regulator in filamentous fungi was found in 2004,regulating the expression of a variety of fungal natural product gene clusters.Besides regulation of beneficial metabolism,fungal toxin biosynthesis and morphological developmental processes,laeA also contributed to activating the expression of cryptic gene clusters and resulted in generating novel secondary metabo...