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微生物学报 2011
Co-existence of resistance genes and their association with the genetic marker of integrons among multi-resistant Escherichia coli isolates
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Abstract:
摘要:【目的】对多重耐药大肠杆菌(Escherichia coli)临床株的β-内酰胺酶类(β-lactamases, BLs)和氨基糖苷钝化酶类(aminoglycoside modifying enzymes, AMEs)耐药基因与Ⅰ-Ⅲ类整合子遗传标记基因之间的相关性进行研究。【方法】采用VITEK-GNS药敏卡测定136株E. coli对14种抗菌素的敏感性;纸片扩散法确认超广谱β-内酰胺酶(extended-spectrum beta-lactamases, ESBLs)产酶株;PCR法检测BL