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The regulation of σB activity and its role in some gram-positive food-borne pathogens——A review
Sigma B因子活性的调节及其在几种革兰氏阳性食源性致病菌中的作用

Keywords: sB,Gram-positive food-borne pathogens,stress response,regulation,bacterial virulence
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Abstract:

The alternative sigma factor sB modulates the stress response of several Gram-positive bacteria. Not only does sB play a prominent role in sporulation in the Gram-positive model organism Bacillus subtilis, but it also contributes both directly and indirectly to bacterial virulence in the food-borne human pathogens Bacillus cereus, Listeria monocytogenes and Staphylococcus aureus. As sB has been shown to regulate expression of both virulence and virulence-associated genes, it indicates that sB is a key player in pathogen ecophysiology.

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