THE SCREENING OF HIGH-YIELD NISIN PRODUCING STRAINS AND LOCALIZATION OF PRECURSOR NISIN GENE
乳链菌肽高产菌株的选育及其基因定位

A mutant strain AL2 with high yield of nisin was obtained from Lacto-coccus lactis 7962 by treatment with physical and chemical factors. The nisin activities of fermentation medium were 2300-2500 IU/ml. LD50 test results indicated that AL2 strain and its product (nisin) are nontoxic. Hybridization experiments suggested that the presence of precursor nisin gene is on the chromosome.