SCREENING OF STRAINS PRODUCING URSODEOXYCHOLIC ACID FROM LITHOCHOLIC ACID AND IDENTIFICATION OF PRODUCT
转化石胆酸为熊去氧胆酸的菌种筛选和产物鉴定

Fusarium equiseti 90-9 was screened for microbial production ofursodeoxycholic acid from lithocholic acid. The weight yield was 38.1% in the presenceof 0.1% lithocholic acid (W/V) within 96h of cultivation. Determination of severalphysical-chemical characteristics including melting point, specific rotation, infraredabsorption spectrum, nuclear magnetic resonance, mass spectrum and elementcomposition etc indicated that the main product was ursodeoxycholic acid.