Advance in Degrading Side Chain of Sterols of Getting Androst-4-Ene-3, 17-Dione by Microorganism
微生物降解甾醇侧链转化雄甾-4-烯-3,17-二酮的研究进展

Sterols hormones plays an indispensable role in clinic. Androst-4-ene-3,17-dione is a middling product of sterol hormones for which can not be substituted and have an very important regulative effect in organism. We can say that almost of hormonal medicines are made of androst -4-ene-3,17-dione .Recently, many researches showed that some microorganisms have the capacity to carry out the selective side chain degradation of sterols and get androst-4-ene-3,17-dione . This paper described the recent advance of the technique in this area. There still some question in this area should be taken into consideration in industry production.