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微生物学通报 2010
Experimental Approaches and the Development of Virus Entry
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Abstract:
Numerous virus families utilize endocytosis to infect host cells,mediating virus internalization as well as trafficking to the site of replication.The endocytic pathways utilized include clathrin-mediated endocytosis,caveolae,macropinocytosis and non-clathrin,non-caveolae pathways.The tools to study endocytosis and,consequently,virus entry are becoming more effective and specific as the amount of information on endocytic component structure and function increases.Now,the use of inhibitory drugs,although sti...