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微生物学通报 2011
Analysis of regulation role of sRNA (istR) in Salmonella resistant to reactive nitrogen and oxygen intermediates
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Abstract:
Salmonella is a facultative intracellular pathogen that is associated with gastroenteritis,sep-ticemia,and typhoid fever.It survives and replicates in macrophages during the course of infection and can be exposed to a number of stressful environments during its life cycle.Among the major antimicro-bial products of macrophages are reactive intermediates of the oxidation of nitrogen(RNI) and the re-duction of oxygen(ROI) which belong to oxygen-dependent antimicrobial systems of phagocytic cells.Resistance to ...