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微生物学通报 2009
Research Progress on PLGA Nanoparticles/Microspheres as DNA Carriers
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Abstract:
Biodegradable PLGA poly(lactide-co-glycolide acid)] have shown significant potential for sustained and targeted delivery of several pharmaceutical agents, including DNA. We reviewed the formulating approaches of PLGA nanoparticles/microspheres as DNA carriers and utilization for gene therapy and vaccine adjuvant.