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OALib Journal期刊
ISSN: 2333-9721
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A Review: the Molecular Mechanisms of InlA- and InlB-mediated Invasion of Listeria monocytogenes into Host Cell
InlA和InlB介导单核细胞增生李斯特菌入侵宿主细胞分子机制的研究进展

Keywords: Listeria monocytogenes,Internalins,Host barriers,Molecular mechanisms
单核细胞增生李斯特菌
,内化素蛋白,宿主屏障,分子机制

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Abstract:

Gram-positive food-borne pathogen Listeria monocytogenes can invade non-phagocytic cells of the hosts by means of the special surface proteins and cause severe systemic infections. Internalins play a key role for Listeria monocytogenes in invading the non-phagocytic cells. In this study we will review and expand upon the recent advances in understanding the molecular mechanisms of InlA- and InlB- mediating the invasion of Listeria monocytogenes into host cells. This paper will also provide the theoretical base for pathogenetic mechanisms, precaution and therapy of food-borne pathogens.

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