A Discussion on Individual Difference between Polymorphism of Mononucleotides and Syndromes of Traditional Chinese Medicine
论单核苷酸多态性与中医证的个体差异

Mononucleotide is the basic component unit of genes and its polymorphism means the difference and diversity of different individuals, which are formed due to the hereditary variation caused by the different orders of the sequence of mononucleotides between two individuals. The polymorphism of mononucleotide constitutes the main factor that determines the individual difference of human beings and is incurred by hereditary variation. The individual difference is characterized by the relative diviation of individual functions so as to keep their dynamic stability. It is a potentialy pathologic factor and the diseases caused by it have the characteristics of physique. Syndromes are based on physique while physique demonstrates itself in the form of syndromes. The characteristics of syndromes contain those of physique and syndromes usually transfer according to physique. The individual difference of syndromes is related to the polymorphism of mononucleotides and this is the best cutting point in the study on the combination of traditional Chinese and Western medicine. The principles of prevention and treatment of diseases by traditional Chinese medicine can be expounded by the establishment of the science of mononucleotide group of syndromes and medicine, thus realizing the ideal of individualized medical treatment and embodying the ideology of searching for the primary cause of diseases in treatment and the prevention and treatment of future diseases.