Pharmacokinetic Variations in Beagle Dog's Plasma after Orally Given Two Chinese Medicinal Herbs Prepared Differently Based on the Same Formula for Treating the Irritable Bowel Syndrome,and Its Significance
IBS中药复方不同方法制备样品的比格犬灌胃给药吸收入血成分定性差异及其意义

Authors qualitatively analyzed the variations of medicinal ingredients in beagle dog's plasma,after given orally the products made from the same formula,but prepared in a different way. In the study,Beagle dog's plasma samples were analyzed,after treated by liquid extraction in a Waters HPLC system equipped with the PDA detector. The mobile phase was either made up of methanol water,or acetonitrile and water. The retention time of HPLC,and UV spectrum were used the qualitative criteria for judging the ingre...