Clinical Research on TCM Syndrome Differentiation of 218 Patients with Postoperative Colorectal Cancer
218 例大肠癌根治术后中医辨证规律的临床研究

The study was aimed to provide objective and scientific evidences in the treatment determination based on pathogenesis obtained through traditional Chinese medicine (TCM) syndrome differentiation. Symptoms and signs of postoperative early metaphase colorectal cancer were objectively summarized and differentiated by TCM syndrome differentiation. Mathematical statistics and multivariate analysis were applied in the clinical research. A total of 218 patients with postoperative early metaphase colorectal cancer were investigated in both Beijing and Shanghai. The contents included common data, TNM staging, and the grade of oncopathology, previous treatment, symptoms, physical sign and TCM syndrome differentiation pattern. The database was established and managed with EPIdata 3.1.The data was twice-enter as auditing. Main statistical methods were multivariate analysis, including cluster analysis and factor analysis. Regular TCM syndrome pattern of postoperative early metaphase colorectal cancer were summarized objectively by mathematical statistics and in combination with clinical practice. Through clinical investigation and mathematical statistics, diagnostic criteria of TCM syndrome differentiation of postoperative early metaphase colorectal cancer were made initially. The seven determined TCM syndrome patterns are the syndrome of dryness of the intestine, the syndrome of insufficient of spleen and stomach, the syndrome of deficient and exhaustion of spleen-qi,the syndrome of deficiency and exhaustion of liver-yin and endoretention of damp heat, the syndrome of incoordination between the liver and stomach, the syndrome of deficiency and exhaustion of kidney-qi, and the syndrome of yang asthenia and phlegmatic hygrosis. Meanwhile, main symptoms and minor symptoms were also defined in each of the seven patterns. It is concluded that according to results of mathematical statistics in combination with TCM theories, there are rules in the TCM syndrome patterns of postoperative colorectal. Further studies should be conducted in this area.