Experiments on Antitumor Activity of Scutellaria Barbata Polysaccharides and Its Immunological Mechanisms
半枝莲多糖的抗肿瘤作用及其调节免疫的实验研究

This research aimed to study the antitumor activity and immunological mechanisms of Scutellaria barbata polysaccharides (SPS). Hepatocarcinoma H22 bearing mice were randomly divided into negative control group, SPS group, and polyporus polysaccharide group. After the drug administration in 10 consecutive days, the inhibitory rate of tumor, thymus index and spleen index, and phagocytic function of macrophage were observed. ELISA method was used in the determination of the serum level of IL-2. The comparison was made among groups. The results showed that SPS can effectively inhibit the growth of HepA. The inhibitory rate of tumor is 34.35%. The weight of immune organ was also increased among HepA -bearing mice. The serum level of IL -2 and phagocytic function of macrophage were also increased. It is concluded that SPS has obvious antitumor activity. The mechanism is due to the enhancement of immune function.