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世界科学技术-中医药现代化 2010
Relationship between the Gensini Score of Blood Stasis Syndrome in Coronary Heart Disease and VEGF
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Abstract:
This work aimed to discuss the relationship between the Gensini score of blood stasis syndrome in coronary heart disease and VEGF. 96 patients with blood stasis syndrome in coronary heart disease were dialectically divided into 48 cases of qi asthenia and blood stasis and 48 cases of intermingled phlegm and blood stasis respectively. Coronary angiography was performed and VEGF was determined. At the same time, the extent of blood stasis was assessed with the blood stasis score, and the result of coronary angiography was assessed with Gensini score system. The blood stasis score and the coronary artery stenosis in qi asthenia and blood stasis were higher than that in intermingled phlegm and blood stasis; the levels of serum VEGF and ET-1 increased with the increase of the blood stasis score and Gensini score; while the level of IGF-1 decreased with the increase of the blood stasis score and Gensini score. The results show that the coronary Gensini score is in correlation with VEGF and blood stasis score.