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世界科学技术-中医药现代化 2005
Application of Capillary Electrophoresis to Separation of Chiral Drugs
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Abstract:
Capillary electrophoresis is a chromatographic technology with high efficiency and selectivity, which carries out separation by taking capillary tubes for separation passage and high voltage electricity for motive force and in accordance with the difference of mobility and distribution behaviors of all the components of samples. It has unique merits in the separation and analysis of chiral drugs and is widely used in the areas of agriculture, medicine and chemical engineering. This article summarizes the application of capillary electrophoresis to the main modes of separation of chiral compounds in the last years. It can be foreseen that this technology will be applied more and more widely in the area of life science, and the analysis of monocells by capillary electrophoresis in particular is becoming a means of in vivo detection in pharmacology at the cellular level and in understanding the process of life.