Screening Bioactive Protein and Peptides in Animal Medicine of Chinese Materia Medica by Proteomics and Peptidomics
基于蛋白质组学、肽组学的中药动物药活性组分的研究

Chinese Materia Medica (CMM) is composed of plants, animals and minerals. Compared with herbal medicine, most bioactive components in animal medicine are macromolecules, such as proteins and peptides. Although many bioactive proteins and peptides have been revealed from animal medicine, it is still a time-costing and labor-consuming work to separate and purify proteins and peptides from the extraction mixture of animal medicine. Proteomics and peptidomics are high-throughput approaches in proteome and peptide analysis. Hence, both methods are applied on screening bioactive proteins and peptides of animal medicine in this study. Progress of the application of proteomics and peptidomics on bioactive proteome and peptides in CMM animal medicine are reviewed in this article.