Estrogen and Progesterone Receptors'Mrna Level Expression Variation in Different Brain Areas of Rat Models
大鼠模拟经前期综合征肝气逆证不同脑区E2受体、P受体基因表达mRNA水平变化

This paper discusses the relationships between liver controlling dredging and both Estrogen and Progesterone receptors' expression. Authors observe both Estrogen and Progesterone receptors' expression variations across different CNS areas (lower part of Thalamus, Border leaf), using molecular biological technique. They found that when liver controlling dredging leads to a Liver- qi invasion, gene expressions of both Estrogen and Progesterone receptors would be reduced in a noticeable manner. Progesterone receptor has a reduced gene expression mainly in the lower part of Thalamus, while Estrogen receptor mainly in the Border leaf. It is concluded that the reduced gene expression of Progesterone and Estrogen receptors can be used as an indicator for diagnosing Liver- qi Invasion.