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世界科学技术-中医药现代化 2008
Salvia Miltiorrhiza and Its Potentials in Ameliorating Multiple Insults in Microcirculatory Disturbance and Target Organ Injuries by Ischemia and Reperfusion
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Abstract:
Ischemia and reperfusion (I/R) makes a prime pathological basis for the injuries originated from trauma,thrombol- ysis,precutaneous transluminal coronary angioplasty,organ transplantation,and hypovolemic shock with resuscitation. I/R elicits multiple insults in microcirculation,including production of peroxides,damage to vascular endothelium,en- hanced leukocyte adhesion,leakage of albumin from vessels,mast cell degranulation,and release of proinflamatory mediators.Numerous published studies have focused on...