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世界科学技术-中医药现代化 2008
The Attenuation Effects of Single Dose Cardiotonic Pills on Myocardial Blood Flow and Myocardial Damage Induced by Myocardial Ischemia Reperfusion
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Abstract:
This study examined the effects of single dose CP on I/R-induced rat myocardial blood flow and myocardial damage.In the study,male SD rats were anesthetized by sodium urethane,before performing the left thoracotomy.The left anterior descending coronary artery was occluded for 30 rain using a 3/0 silk suture,and the blood flow was subsequently released (I/R).The coronary blood flow was monitored by laser Doppler flowmetry before ischemia and 60min after reperfusion.The infarct size was determined by tetrazol...