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Preparation of Dissolving - out Rate and Bioactivity of Three Chinese Medicinal Herbs by Micro - technology and Comparative Study of Their in vivo Dynamics-Exploration of Micron Chinese Medicine
微细化工艺制备三种中药的溶出度、生物活性及体内动力学比较研究——微米中药应用探讨

Keywords: 微米中药,超微粉碎,三七,葛根,知母,溶出度,体内动力学,生物活性

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Abstract:

To fully know the characteristics of the preparation of Chinese herbal medicine by micro - technology so as to better the use of this technology a comprehensive experiment of in vitro dissolving - out and in vivo absorption as well as the bioactivity and safety of prepared fine powders of three Chinese medicinal herbs-pseud - ginseng, the root of kudzu vine and rhizoma anemarrhenae has been carried out and all the indications of them have been compared respectively with those of the powders of the said three medicinal herbs prepared according to the method assigned in the 2000 edition of the Chinese Pharmacopoeia. The result indicates that the dissolving - out rate of the effective components of the said three medicinal herbs can be improved in its degree when the herbs are worked into fine powders, and then their release and absorption in human body can speed up and in a given degree their original activity can be kept without apparent increase of toxicity. The study shows that the advantages of Chinese medicinal materials prepared by micro - technology can be demonstrated in the dissolution of their effective components, but in the practical application this technology should be used in accordance with the physico - chemical properties of the medicinal materials to be prepared and on a selective basis.

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