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Role of Platelet-Monocyte Aggregation in the Onset of Acute Cardiovascular and Cerebrovascular Diseases
血小板单核细胞聚集体在急性心脑血管疾病发病中的地位

Keywords: Atherosclerosis,platelet-lymphocyte aggregates,cardiovascular and cerebrovascular diseases,adhesion
动脉粥样硬化
,血小板单核细胞聚集体,心脑血管疾病,粘附

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Abstract:

Atherosclerosis is the main pathological basis of cardiovascular and cerebrovascular diseases. Adhesion and aggregation of platelet and monocyte play an important role in patients with acute cardiovascular and cerebrovascular diseases. This article reviewed molecular mechanism of aggregation formation, mechanism of inducing plaque rupture, pathogenesis of impacting acute cardiovascular and cerebrovascular disease occurrence, targets of Chinese medicine and western medicine, and corresponding monoclonal antibodies and gene knockout, etc. Problems existed in the current study were also analyzed in order to arouse the attention of fellow researchers.

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