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OALib Journal期刊
ISSN: 2333-9721
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Pharmacokinetics of Sustained Release Total Puerariaeflavones
葛根总黄酮缓释片药动学研究

Keywords: total puerariae flavones,puerarin,sustained release tablets,drug plasma level,beagle dog
葛根总黄酮
,葛根素,缓释片,血药浓度,比格犬

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Abstract:

Authors studied the sustained release tablets of total puerariae flavones in vivo. In the study, Yu Feng Ning Xin tablet was taken as a reference, and the release process of the sustained release tablet was analyzed in vivo. HPLC method was employed to determine the concentration of pueratin in plasma, and to test the releases in five healthy beagle dogs. Compared with Yu Feng Ning Xin tablet, the sustained release of total puerariae flavones allowed an obviously sustained release in vivo. It is concluded that the sustained release tablet of total pueratiae falvones has been up to the design requirements.

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