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世界科学技术-中医药现代化 2007
Pharmacokinetics of Sustained Release Total Puerariaeflavones
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Abstract:
Authors studied the sustained release tablets of total puerariae flavones in vivo. In the study, Yu Feng Ning Xin tablet was taken as a reference, and the release process of the sustained release tablet was analyzed in vivo. HPLC method was employed to determine the concentration of pueratin in plasma, and to test the releases in five healthy beagle dogs. Compared with Yu Feng Ning Xin tablet, the sustained release of total puerariae flavones allowed an obviously sustained release in vivo. It is concluded that the sustained release tablet of total pueratiae falvones has been up to the design requirements.