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Comparison of Effects of Salvia Miltiorrhiza Bge. fromDifferent Habitats by Cluster Analysis and Matrix Sum
用聚类—矩阵和法评价不同产地丹参提取物相关活性

Keywords: salvia miltiorrhiza Bge,Pharmacodynamics,cluster analysis,matrix sum
丹参
,药效学,聚类分析,矩阵和法

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Abstract:

Objective: To compare the total effects of Salvia miltiorrhiza Bge. from different localities. Methods: ADP-induced platelet aggregation and thrombogen time and MDA in rats' brain in vitro have been determined, and cluster analysis and comprehensive evaluation method have also been used to evaluate the total effects of Salvia miltiorrhiza Bge. Results: Active components of Salvia miltiorrhiza Bge. have inhibited ADP-induced platelet aggregation, retarded blood-plasma coagulation induced by Ca2+-cephalin and reduced the MDA in rats' brain in vitro. Conclusion: The results indicate that the wild Salvia miltiorrhiza Bge. from Shanxi province is the best one among the 8 varieties and then the planting ones in Sichuan, wild ones in Shandong and planting ones in Henan. The wild Salvia miltiorrhiza Bge. in Ankang county of Shanxi Province and in Lu county of Henan province are the worse.

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