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实验力学  2011 

Recent Progress in Cellular Traction Force Microscopy Inversion Methods
细胞牵引力显微镜反演方法研究进展

Keywords: cell,elastic substrate,traction force microscopy,digital image correlation,ill-posed inverse problem,regularization
细胞
,弹性基底,牵引力显微镜,数字图像相关,病态反问题,正则化

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Abstract:

Physical and mechanical interaction between cell and extracellular matrix in a microenvironment involves a large number of complex signaling transduction pathways,so it plays a key role in mediating cellular behaviors and functions such as cell proliferation,differentiation,contraction,migration and apoptosis.It is very important,both physiologically and pathologically,to quantitatively characterizing single cell activities based upon cellular traction force microscopy(CTFM).The core of CTFM consists in how...

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