Effect of triphenyltin on the muscle histology in crucian carp larva
三苯基锡对鲫稚鱼肌肉组织学的影响

Triphenyltin (TPT) and tributyltin (TBT) often co-exist in the environment. However, far fewer studies addressing the toxicity of TPT on fishes are available than for TBT. The present study was conducted to investigate the effects of TPT at environmentally relevant concentrations (10,100 and 1000 ng/L) on muscle histology in crucian carp larva (Carassius auratus auratus) which is a common and economic-important fish in freshwater. After exposure for 16 days, serious damage of muscle was found, which is shown as increases of interstitial space, fracture of muscle fibers and changes of glycogen. Furthermore, the damage of muscle is the most notable in the 100 ng/L TPT group. In addition, the 100 ng/L TPT significantly reduced the muscle fibers diameter and induced a remarkable glycogen accumulation. On the contrary, the 1000 ng/L TPT significantly increased the muscle fibers diameter and reduced the glycogen levels compared with the control. The results provided new information which is important for fully understanding the toxicity of TPT.