The preliminary studies on the accumulation and depuration of microcystins, a cyanobacterial toxin, in Tilapia fish
太湖微囊藻毒素在罗非鱼体内的累积及生物降解的初步研究

In order to understand the accumulation and distribution of microcytins (MCs) in Tilapia fish during a cyanbobaeterial bloom from June 2008 to August 2008.The MCs contents of water sample and fish sample in the Pond and Cage were determined by enzyme-linked immunosorbent assay (ELISA). The concentration was expressed as microcystin-LR equivalent. The result demonstrated the MC-LR concentration of water in the pond, positively correlated with the density of cyanobacteria, was from 0.123 to 0.514 ug/L. and the MC-LR concentration of the control was higher than the ones of the experiment. The concentration of MC-LR in muscle tissue is between 1.194 and 3.615ng/g. Comparing the MC-LR concentration of the muscle, the higher MC-LR accumulation in the liver occurred in the ponds. Then the Tilapia fishes in the pond and the cage were transferred to new environment without the microcytins of cyanbobaeterial bloom. The microcystins contents of the liver and muscle samples were detected by ELISA. The concentration of MC-LR in muscle tissue was presented bellow the recommended tolerable daily intake of MC-LR by humans. But the concentration of MC-LR in liver tissue needed 10 to 20 days biodegrading to get to the safely acceptable daily intake for MC-LR. The food chain accumulation and organ distribution of microcystins in Tilapia fish were here in discussion.