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OALib Journal期刊
ISSN: 2333-9721
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DOWN REGULATION OF INSULIN AND GM-CSF RECEPTORS IN MURINE BONE MARROW CELLS AND PERITONEAL MACROPHAGES AFFECTED BY FORSKOLIN
毛喉萜对小鼠骨髓细胞和腹腔巨噬细胞表面胰岛素受体和GM-CSF受体的下调作用

Keywords: Forskolin,Insulin,Granulocte-Macrophage Colony,Stinulating Factor (GM -CSF),Receptor
毛喉萜
,胰岛素,粒细胞,巨噬细胞,集落刺激因子

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Abstract:

Radioreceptorassay showed that forskolin could down regulate the nnmbers of insulin and granulocyte-macrophage colony stimulating factor(GM-CSF)receptors in murine bone marrow cells and peritoneal macrophages. And the effect on GM-CSF receptors appeared in a dose and the dependent fashion. The macrophages have showed am increase of acidic phosphatase activity and more stretchy microfilaments after being treated with FSK.

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