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生态毒理学报 2012
Research Advances in Toxicology of DEHP and Its Health Effects
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Abstract:
As an important plasticizer for polyvinyl chloride plastics, DEHP was widely used in industry, which was currently detected in the ocean, air, drinking water, animals and plants to different extent. DEHP has caused ever-increasing ecological environment pollution. In this paper, the domestic and foreign toxicological researches were reviewed, which were related to the human exposure and metabolic pathways of DEHP. The toxicity and potential danger of DEHP to animals and human health were discussed in detail from the aspect of liver, heart, reproductive/developmental system and respiratory system. On these bases, the existing problems and further research directions were pointed out.