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PLOS ONE  2012 

The Effect of Surface Nanometre-Scale Morphology on Protein Adsorption

DOI: 10.1371/journal.pone.0011862

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Abstract:

Protein adsorption is the first of a complex series of events that regulates many phenomena at the nano-bio interface, e.g. cell adhesion and differentiation, in vivo inflammatory responses and protein crystallization. A quantitative understanding of how nanoscale morphology influences protein adsorption is strategic for providing insight into all of these processes, however this understanding has been lacking until now.

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