Toxicity of Cu2+ to Juvenile Perch Lateolabrax maculatus
铜离子对中国花鲈幼鱼的毒性研究

In order to provide data of pollution biology for the perch (Lateolabrax maculatus) culture, the toxic symptom and LC50 were studied in the juvenile perch exposed to Cu2+. The levels of GSH and MDA and activities of SOD, CAT, GOT and GPT were examined; The effects of Cu2+ stress on the total dyskaryosis and micronuclear rates of the juvenile erythrocytes were analyzed. The results showed that LC50 for juvenile exposed to Cu2+ for 24, 48, 72 and 96 h was 1.85, 1.66, 1.48 and 0.86 mg·L-1, respectively. The liver tissue of agonal individuals necrosed and a mass of blood sinuses occurred in the gill tissue. GSH, MDA, SOD, GPT and GOT in the liver were sensitive, while CAT was not sensitive to Cu2+ stress. Exposed to Cu2+ at concentration of 0.42 mg·L-1 for 96 h, total dyskaryosis and micronuclear rates of the juvenile erythrocytes in the treated groups were significantly higher (p<0.05) than that in the control. Cu2+ stress not only damaged the liver antioxidant system, liver and gill tissues, but also had definite genetic toxity to the juvenile perch.