Approximate Entropy Based on Wavelet Transforms of Brainstem Auditory Evoked Potential of Infantile Spasms
基于小波变换的婴儿痉挛症脑干听觉诱发电位复杂性分析

Infantile spasm is a refractory epilepsy with a significant characteristics of mental retardation. Based on multiscale wavelet transforms of brainstem auditory evoked potential of infantile spasms approximate entropy was used to find out whether brainstem should be responsible for this phenomenon. 25 patients under observation were divided into 2 groups, which 12 cases in the normal group and 13 cases in the infantile spasms group. All these brainstem auditory evoked potentials were recorded. Approximate entropies base on wavelet coefficients in 60 scales, which are calculated by Gauss. Although there was no different during 0~10 ms in 60 scales between normal and infantile spasms group, significant different statistically appeared in 3~7 ms (P<0.01), which represented the action of the brainstem, especially in lower scales. The existent of jams and cracks in brainstem transfer pathway of infantile spasms and the decrease or excessive delay of the effective information to cerebral cortex really give rise to the mental retardation in the children suffering from infantile spasms.