SYNAPTIC PLASTICITY IN THE OUTER PLEXIFORM LAYER OFCARP RETINA AND MODEL ANALYSIS
鲫鱼外层视网膜突触强度可塑性及模型分析

The spectral sensitivity of luminosity type retinal horizontal cell (LHC) is stimulus pattern dependent. A mathematical model is developed in this study to investigate the possible physiological mechanism underlying such phenomenon. The model consists of two parallel signal pathways, which are the red- and green-cone signal pathways respectively. The strength of synapses between the relevant neurons of each signal pathway is represented by its gain term; a linear summation of the output of each pathway forms the system output, which represents the LHC's light response. With the assumption that the status of each pathway is modifiable, i.e., the gain of each pathway is positively related to its current status and negatively related to the system output, the model prediction describes the experimental observations reasonably well.