Studies of Raman Spectroscopy on the Interaction of Silica with Phospholipid Liposome
二氧化硅与脂质体相互作用的激光拉曼光谱研究

Liposomes which have undergone silica action give us a Raman spectrum, in which the intensity ratio of 1127cm-1 to 1093cm-1 bands decreases, so does the intensity ratio of 2883cm-1 to 2847cm-1 bands.The 715cm-1 band shifts about 2-3cm-1 toward the lower frequency and its intensity decreases, while its width increases.The facts show that silica can react significantly with phospholipids and form a atable complex with polar head groups of phospholipids. The change of alkyl chain conformation is caused by the interaction of silica with the heads of phospholipids and deformation of liposomes.As for titantium dioxide,it acts on Liposomes very little and can not cause the change of Raman sqectrum.