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生物物理学报 2010
Angiogenesis: A Promising Strategy for Tumor Therapy
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Abstract:
Inhibiting angiogenesis is a promising strategy for treatment of cancer, whoes aim is to block tumor blood vessels and allow tumor die from starvation. In 1971 Folkman hypothesed that tumor growth is angiogenesis-dependent. In 2004 the first antiangiogenesis drug received approval from the US FDA for cancer treatment. Angiogenesis is now a hot area of tumor biology. Various novel targets, mechanism and inhibitors have been found. This review will focus on recent progress of these projects providing insight into angiogenesis research.