A SIMULATION STUDY ON EFFECTIVE PARAMETERS TO REPRESENT THE HETEROGENEITY IN VENTRICULAR REPOLARIZATION
表征心室复极不一致有效参数的仿真研究

A one-dimension model of myocardium from endocardium to epicardium was established. The heterogeneity of ventricular repolarization was produced by changing the ischemic degree, in which the electrogram was calculated by different method. The QT dispersion and ARI (activation recovery interval) dispersion was then obtained. It showed that there was no obvious difference in QT interval between ischemic region and normal region, thus QT dispersion was close to zero. It can not effectively represent the heterogeneity in ventricular repolarization. However, there was an obvious difference in ARI between ischemic region and normal region, and the ARI dispersion was proportional to ischemic degree. Therefore it can effectively represent the heterogeneity in ventricular repolarization.